11/12/25

MDMA, Sex, and Social Anxiety: The Neuroscience of Loneliness and Connection | Ben Rein

In this illuminating episode, Dr. Gabrielle Lyon sits down with award-winning neuroscientist Dr. Ben Rein to explore the biology of human connection and why our brains are wired for social bonding. Dr. Rein breaks down groundbreaking research on loneliness, showing it can be as harmful as smoking, and explains how modern screen-based communication alters empathy, emotion, and cognitive health. Together, they dive into the neurochemistry of relationships, the therapeutic science behind MDMA and ketamine, the psychology of likability, and why AI can never truly replicate human intimacy. This conversation delivers a powerful, science-backed look at the molecules, behaviors, and habits that shape happiness, resilience, and long-term brain performance.

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